Product Description

SPRTN Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-52495-60, E-AB-52495-120, E-AB-52495-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SPRTN

Target Synonym: C1orf124; CA124; Chromosome 1 open reading frame 124 ; DDDL1880; dJ876B10.3; PRO4323; RP5-876B10.3; Spartan; SprT-like domain at the N terminus; SprT-like N-terminal domain; Zinc finger RAD18 domain-containing protein C1orf124

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9H040

Background: The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.

Concentration: 1 mg/mL

Immunogen: Fusion protein of human SPRTN

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only