SRPK2 Polyclonal Antibody - BT-AP14483

SRPK2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14483-20, BT-AP14483-50, BT-AP14483-100

Citations, Manuals and MSDS Available upon request.

Background: Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Ser-52 and Ser-588.,Phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.,sequence The cDNA appears to contain a duplicated region.,Belongs to the protein kinase superfamily.,Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.,Contains 1 protein kinase domain.,tissue specificity:Highly expressed in brain, moderately expressed in heart and skeletal muscle and at low levels in lung, liver, and kidney.,

Research Areas: Epigenetics and nuclear signaling; Cell biology

Target Protein: SRPK2

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: SRSF protein kinase 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P78362; Mouse: O54781

Synonyms: SRSF protein kinase 2;EC 2.7.11.1;SFRS protein kinase 2;Serine/arginine-rich protein-specific kinase 2;SR-protein-specific kinase 2 [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protei

GeneID: Human: 6733

Research Use Only