Product Description

SSBP1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES3502-50, ES3502-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010],

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: SSBP1, SSBP, Single-stranded DNA-binding protein, mitochondrial, Mt-SSB, MtSSB, PWP1-interacting protein 17

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human MtSSB. AA range:99-148

Isotype: IgG

Target: SSBP1

Specificity: SSBP1 Polyclonal Antibody detects endogenous levels of SSBP1 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in retinal ganglion cells, photoreceptors, pigmented epithelium and fibroblasts (at protein level),

Observed Band (KD): 17kD

Fields: DNA replication, Mismatch repair, Homologous recombination

Function: Function: This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR
Similarity: Contains 1 SSB domain
Subunit: Homotetramer

Subcellular Location: Mitochondrion Mitochondrion matrix, mitochondrion nucleoid

Storage and Stability: -20°C/1 year

Gene Name: SSBP1

Protein Name: Single-stranded DNA-binding protein mitochondrial

Mouse Gene ID: 381760

Mouse SwissProt Number: Q9CYR0

Rat Gene ID: 54304

Rat SwissProt Number: P28042

Research Use Only