ST5 Polyclonal Antibody - BT-AP08597

ST5 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08597-20, BT-AP08597-50, BT-AP08597-100

Citations, Manuals and MSDS Available upon request.

Background: ST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. Suppression of tumorigenicity 5 protein encoded by ST5 contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

Research Areas: Signal Transduction

Target Protein: ST5

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: ST5 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 126499

UniProt Accession: Human: P78524; Mouse: Q924W7

Synonyms: ST5; DENND2B; HTS1; Suppression of tumorigenicity 5 protein; DENN domain-containing protein 2B; HeLa tumor suppression 1

GeneID: Human: 6764; Mouse: 76954

Research Use Only