STAT4 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2638-20, A2638-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 86kDa
Observed Molecular Weight: 93kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 6775
SWISS: Q14765
Alternate Names: SLEB11; STAT4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Protein phosphorylation, Signal Transduction, ErbB-HER Signaling Pathway, Immunology Inflammation, Jak-Stat-IL-6 Receptor Signaling Pathway.
NCBI Alias: STAT4
Research Use Only