Product Description

STEAP1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES3521-50, ES3521-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: STEAP1, PRSS24, STEAP, Metalloreductase STEAP1, Six-transmembrane epithelial antigen of prostate 1

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human STEAP1. AA range:31-80

Isotype: IgG

Target: STEAP1

Specificity: STEAP1 Polyclonal Antibody detects endogenous levels of STEAP1 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Ubiquitously expressed, Highly expressed in prostate tumors,

Observed Band (KD): 36kD

Fields: Mineral absorption

Function: Cofactor: FAD
Function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor
Similarity: Belongs to the STEAP family
Similarity: Contains 1 ferric oxidoreductase domain
Tissue Specificity: Ubiquitously expressed. Highly expressed in prostate tumors

Subcellular Location: Endosome membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: STEAP1

Protein Name: Metalloreductase STEAP1

Mouse SwissProt Number: Q9CWR7

Research Use Only