Product Description

Stra8 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES4287-50, ES4287-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, IHC

Alternate Names: STRA8, Stimulated by retinoic acid gene 8 protein homolog

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human STRA8. AA range:151-200

Isotype: IgG

Target: Stra8

Specificity: Stra8 Polyclonal Antibody detects endogenous levels of Stra8 protein.

Dilution: WB 1:500-2000, IHC-p 1:50-300

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed specifically in testis and fetal ovaries,

Observed Band (KD): 66kD

Function: Function: Required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase
PTM: Phosphorylated
Tissue Specificity: Expressed specifically in testis

Subcellular Location: Cytoplasm Nucleus Shuttles between nucleus and cytoplasm Nuclear export is XPO1-dependent

Storage and Stability: -20°C/1 year

Gene Name: STRA8

Protein Name: Stimulated by retinoic acid gene 8 protein homolog

Mouse SwissProt Number: P70278

Research Use Only