Product Description

STX7 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES12887-50, ES12887-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome. [provided by RefSeq, May 2016],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human STX7 AA range: 42-92

Isotype: IgG

Target: STX7

Specificity: This antibody detects endogenous levels of STX7 at Human/Mouse/Rat

Dilution: WB 1:500-2000, IHC-p 1:50-300

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Highest expression is found in placenta followed by heart, skeletal muscle, kidney and brain, Low expression is found in pancreas, lung and liver,

Molecular Weight (Da): 29kD

Fields: SNARE interactions in vesicular transport, Phagosome

Function: Function: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes
Similarity: Belongs to the syntaxin family
Similarity: Contains 1 t-SNARE coiled-coil homology domain
Subunit: Forms a SNARE complex with VTI1B, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Interacts with VPS33A. Found in a complex with VAMP8 and VTI1B in the liver. Part of the SNARE core complex containing VAMP8, STX8 and VTI1B (By similarity). Interacts with VPS11, VPS16 and VPS18
Tissue Specificity: Highest expression is found in placenta followed by heart, skeletal muscle, kidney and brain. Low expression is found in pancreas, lung and liver

Subcellular Location: Early endosome membrane, Single-pass type IV membrane protein

Storage and Stability: -20°C/1 year

Gene Name: STX7

Protein Name: STX7

Mouse SwissProt Number: O70439

Rat Gene ID: 100910446

Rat SwissProt Number: O70257

Research Use Only