SULF1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13797-20, A13797-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.
Synonyms: SULF-1; SULF1
GeneID: 23213
Swiss Prot: Q8IWU6
Tested Applications: ELISA, WB
Reactivity: Human, Rat
Calculated Molecular Weight: 101kDa
Observed Molecular Weight: 101kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 480-610 of human SULF1 (NP_001121676.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Cytoskeleton
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HepG2, MCF7, PC-3, U-251MG, Rat testis
Cellular Location: Cell surface, Endoplasmic Reticulum, Golgi Apparatus, Golgi stack,
Keywords: 23213, SULF1, SULF-1, sulfatase 1, extracellular sulfatase Sulf-1, sulfatase FP, Q8IWU6, Sulfatase 1, Extracellular Sulfatase Sulf-1, Sulfatase FP, EC 3.1.6.-, KIAA1077, HSulf-1
Symbol: SULF1
Category: Polyclonal Antibodies
Research Use Only