SVIL Polyclonal Antibody - RA35132

SVIL Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35132-50, RA35132-100

Citations, Manuals and MSDS Available upon request.

Background: supervillin (SVIL) Homo sapiens This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Several transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Apr 2016],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 6840

Protein MW (KDa): 243

SWISS: O95425

Source: Rabbit

Research Use Only