Product Description

SVIL Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35132-50, RA35132-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: supervillin (SVIL) Homo sapiens This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Several transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Apr 2016],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 243

Protein Molecular Weight (kDa): 243

Storage: -20°C/1 year

Human Gene ID: 6840

Human SwissProt Number: O95425

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only