Product Description

SYAC Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES12871-50, ES12871-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human SYAC AA range: 504-554

Isotype: IgG

Target: SYAC

Specificity: This antibody detects endogenous levels of SYAC at Human/Mouse/Rat

Dilution: WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.278% sodium azide.

Expression: Epithelium, Liver, Osteosarcoma, Placenta, Renal cell carcinoma,

Observed Band (KD): 105kD

Fields: Aminoacyl-tRNA biosynthesis

Function: Catalytic Activity: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)
Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family
Subunit: Monomer

Subcellular Location: Cytoplasm

Storage and Stability: -20°C/1 year

Gene Name: AARS

Protein Name: SYAC

Mouse Gene ID: 234734

Mouse SwissProt Number: Q8BGQ7

Rat Gene ID: 292023

Rat SwissProt Number: P50475

Research Use Only