Synuclein-α (phospho Tyr133) Polyclonal Antibody - RA30219

Synuclein-α (phospho Tyr133) Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA30219-50, RA30219-100 Citations, Manuals and MSDS Available upon request. Background: synuclein alpha (SNCA) Homo sapiens Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. Alternative Names: SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP Applications: WB; IHC-p; IF (paraffin section) ; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 6622 Protein MW (KDa): 18 SWISS: P37840 Source: Rabbit Research Use Only