T-type Ca++ CP α1H (P492) Polyclonal Antibody-BS3413

T-type Ca++ CP α1H (P492) Polyclonal Antibody

Catalogue Numbers: BS3413-50, BS3413-100

Sizes: 50µl, 100µl

Alternative Name: Voltage-dependent T-type calcium channel subunit alpha-1H; Low-voltage-activated calcium channel alpha1 3.2 subunit; Voltage-gated calcium channel subunit alpha Cav3.2; CACNA1H

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O95180

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Voltage-dependent Ca++ channels mediate Ca++ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an α1 subunit, an intracellular β subunit, a disulfide linked α2/δ subunit and a transmembrane γ subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca++ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca++ current types. T-type Ca++ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: T-type Ca++ CP α1H (P492) polyclonal antibody detects endogenous levels of T-type Ca++ CP α1H protein.

Bioworld Molecular Weight: ~ 315 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of T-type Ca++ CP α1H (P492) pAb at 1:500 dilution
Lane 1: L02 whole cell lysate(40ug)
Lane 2: HepG2 whole cell lysate(40ug)
Lane 3: PC3 whole cell lysate(20ug)
Lane 4: AML-12 whole cell lysate(40ug)
Lane 5: H9C2 whole cell lysate(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 461-510 of Human T-type Ca++ CP α1H.

Conjugate: Unconjugated

Modification: Unmodified