Product Description

T3JAM Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES3547-50, ES3547-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: TRAF3IP3, T3JAM, TRAF3-interacting JNK-activating modulator, TRAF3-interacting protein 3

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human T3JAM. AA range:251-300

Isotype: IgG

Target: T3JAM

Specificity: T3JAM Polyclonal Antibody detects endogenous levels of T3JAM protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Blood, Lung adenocarcinoma,

Observed Band (KD): 64kD

Function: Function: May function as an adapter molecule that regulates TRAF3-mediated JNK activation
Subunit: Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain

Subcellular Location: Cell membrane Golgi apparatus membrane, Single-pass type IV membrane protein Lysosome membrane Mitochondrion outer membrane Accumulates on the mitochondria after virus infection

Storage and Stability: -20°C/1 year

Gene Name: TRAF3IP3

Protein Name: TRAF3-interacting JNK-activating modulator

Mouse Gene ID: 215243

Mouse SwissProt Number: Q8C0G2

Research Use Only