Product Description

TCP-1ζ Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5959-50, BS5959-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 α, β, γ, δ, ε, ζ, η and θ, each encoded by a different gene. Two ζ subunits have been described: TCP-1 ζ (also designated TCP-1 ζ1) and TCP-1 ζ2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubμlins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecμlar chaperone for Actin and Tubμlin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: T-complex protein 1 subunit zeta, TCP-1-zeta, Acute morphine dependence-related protein 2, CCT-zeta-1, HTR3, Tcp20, CCT6A, CCT6, CCTZ, TCP1ζ, TCP 1ζ, TCP1-ζ, TCP-1-ζ, CCT-ζ-1, CCTζ-1, CCT-ζ1, CCTζ1,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 216-261 of Human TCP-1ζ.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TCP-1ζ polyclonal antibody detects endogenous levels of TCP-1ζ protein.

Molecular Weight: ~ 60 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P40227

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only