Product Description

TCR β (K115) Polyclonal Antibody

Catalogue Numbers: BS2943-50, BS2943-100

Sizes: 50µl, 100µl

Alternative Name: T-cell receptor beta-1 chain C region; TRBC1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P01850

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either alpha and beta or gamma and delta chains. The vast majority of circulating T cells (95%) express the alpha/beta heterodimer while roughly 2-5% express the gamma/delta heterodimer. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TCR β (K115) polyclonal antibody detects endogenous levels of TCR β protein.

Bioworld Molecular Weight: ~ 19 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of TCR β (K115) pAb at 1:500 dilution
Lane 1: H1792 whole cell lysate(40ug)
Lane 2: Hela whole cell lysate(40ug)
Lane 3: H9C2 whole cell lysate(40ug)
Lane 4: 3T3-L1 whole cell lysate(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 81-130 of Human TCR β.

Conjugate: Unconjugated

Modification: Unmodified