TGF beta Receptor I (TGFBR1) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0708-20, A0708-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 56kDa
Observed Molecular Weight: 56kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 7046
SWISS: P36897
Alternate Names: AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; TBRI; ALK-5; LDS1A; LDS2A; TBR-i; TGFR-1; ACVRLK4; tbetaR-I; TGF beta Receptor I (TGFBR1)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Growth factors, TGF-b-Smad Signaling Pathway, Endocrine Metabolism, Stem Cells, Cardiovascular, Angiogenesis, Hypoxia.
NCBI Alias: TGFBR1
Research Use Only