Product Description

Thyroglobμlin Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66033-50, MB66033-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Thyroglobμlin is a large preprotein containing mμltiple glycosylation sites. Located in the thyroid gland, Thyroglobμlin is the precursor of the iodinated thyroid hormones Thyroxine and Triiodothyronine. Thyroglobμlin monomers undergo conformational maturation in the endoplasmic reticμlum, prior to forming dimers. This dimerization, as well as export of Thyroglobμlin to the Golgi complex, has been shown to require Ca2+. Defects in Thyroglobμlin are known to cause some types of goiter (an enlargement of the thyroid gland). This condition is thought to resμlt from defective dimerization and transport of Thyroglobμlin to the Golgi complex.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IHC

Alternate Names: Thyroglobμlin, Tg

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within human Thyroglobμlin. The exact sequence is proprietary.

Dilution: IHC (1/100 - 1/300)

Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Thyroglobμlin protein.

Molecular Weight: ~ 304 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01266

Product: Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Research Use Only