TIAM1 Polyclonal Antibody - BT-AP14951

TIAM1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14951-20, BT-AP14951-50, BT-AP14951-100

Citations, Manuals and MSDS Available upon request.

Background: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.,Belongs to the TIAM family.,Contains 1 DH (DBL-homology) domain.,Contains 1 PDZ (DHR) domain.,Contains 1 PH domain.,Contains 1 RBD (Ras-binding) domain.,Contains 2 PH domains.,subunit:Interacts with BAIAP2.,tissue specificity:Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.,

Research Areas: Signal transduction

Target Protein: TIAM1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: T-lymphoma invasion and metastasis-inducing protein 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13009; Mouse: Q60610

Synonyms: T-lymphoma invasion and metastasis-inducing protein 1;TIAM-1

GeneID: Human: 7074

Research Use Only