Product Description

TIMP-1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20789-50, RA20789-100

Citations, Manuals and MSDS Available upon request.

Background: TIMP metallopeptidase inhibitor 1 (TIMP1) Homo sapiens This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: TIMP1; CLGI; TIMP; Metalloproteinase inhibitor 1; Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1

Applications: IF/ICC; WB; IHC-p; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 7076

Protein MW (KDa): 24

SWISS: P01033

Source: Rabbit

Research Use Only