Tissue plasminogen activator from Human, Recombinant, 580,000 IU/mg - NATE-0920

Tissue plasminogen activator from Human, Recombinant, 580,000 IU/mg

Size: 100 ug

Catalogue Number: NATE-0920

Citations, Manuals and MSDS Available upon request.

Product Description: Tissue plasminogen activator (abbreviated PLAT or tPA) is a secreted serine proteasewhich converts the proenzymeplasminogento plasmin, a fibrinolyticenzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked plasmin. This enzyme plays a role in cell migrationand tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysiswhich can result in thrombosisor embolism.

Storage: -20°C

Activity: 580,000 IU/mg

Research Use Only