Product Description

Titin/CMD1G Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65480-50, BS65480-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Titin, also known as connectin, is a large protein involved in the temporal and spatial control of the assembly of the highly ordered sarcomeres (contractile units) of striated muscle. In addition to sarcomere assembly Titin also functions to maintain the structural integrity of the contracting myofibrils within the muscle and to organize the machinery for condensation of chromosomes in dividing cells. Titin is a giant protein composed of 27, 000 amino acids and contains an autoregμlated serine kinase catalytic domain as well as a calcium/calmodμlin binding region that are involved in its activation. Activated Titin phosphorylates the muscle protein telethonin, a sarcomeric protein abundant in heart and skeletal muscle, implicating Titin activity in the reorganization of the cytoskeleton during myofibrillogenesis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Pig, Cow

Host: Rabbit

Applications: ELISA, IHC

Alternate Names: TTN, MPRM, Cardiomyopathy dilated 1G (autosomal dominant), CMD1G, CMH 9, CMH9, CMPD 4, CMPD4, Connectin, DKFZp451N061, EOMFC, HMERF, LGMD2J, MU RMS 40.14, Rhabdomyosarcoma antigen, Rhabdomyosarcoma antigen MU RMS 40.14, Rhabdomyosarcoma antigen MU-RMS-40.14, TITIN_HUMAN, TMD.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: KLH conjugated synthetic peptide derived from human Titin/CMD1G:2601-2800/34350

Dilution: ELISA=1:5000-10000
IHC=1:100-500

Purification: affinity purified by Protein A

Specificity: Titin/CMD1G Polyclonal Antibody detects endogenous levels of Titin/CMD1G protein.

Molecular Weight: 3780 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8WZ42

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only