TLX1 Polyclonal Antibody - BT-AP15010

TLX1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15010-20, BT-AP15010-50, BT-AP15010-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.

Research Areas: Epigenetics and nuclear signaling; Developmental biology

Target Protein: TLX1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: T-cell leukemia homeobox protein 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P31314; Mouse: P43345

Synonyms: T-cell leukemia homeobox protein 1;Homeobox protein Hox-11;Proto-oncogene TCL-3;T-cell leukemia/lymphoma protein 3

GeneID: Human: 3195

Research Use Only