TM2D1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA35376-50, RA35376-100 Citations, Manuals and MSDS Available upon request. Background: TM2 domain containing 1 (TM2D1) Homo sapiens The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016], Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000 Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse GeneID (Human): 83941 Protein MW (KDa): 22 SWISS: Q9BX74 Source: Rabbit Research Use Only