TM2D1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA35376-50, RA35376-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: TM2 domain containing 1 (TM2D1) Homo sapiens The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016], Reactivity: Human, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 22 Protein Molecular Weight (kDa): 22 Storage: -20°C/1 year Human Gene ID: 83941 Human SwissProt Number: Q9BX74 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only