Product Description

TMEM43 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46522-50, BS46522-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricμlar dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricμlar cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricμlar dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricμlar tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq, Oct 2008]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: LUMA, ARVC5, ARVD5, EDMD7

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human TMEM43

Dilution: WB: 1:1000-1:5000 IHC: 1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9BTV4

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only