Product Description

TNF α Monoclonal Antibody (Q36)

Sizes: 50μL, 100μL

Catalogue Numbers: RA10578-50, RA10578-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: tumor necrosis factor (TNF) Homo sapiens This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse

Host: Mouse

Applications: WB, IHC-p, IF(paraffin section)

Alternate Names: Tumor necrosis factor (Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment, NTF), Intracellular domain 1 (ICD1), Intracellular domain 2 (ICD2), C-domain 1, C-domain 2, Tumor necrosis factor, soluble form]

Clonality: Monoclonal

Dilution: WB: 1:1000-1:3000 IHC: 1:50-1:200

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 7124

Protein Molecular Weight（KDa): 17, 25

Molecular Weight: 17, 25

Research Use Only