TNF α Polyclonal Antibody - RA30579

TNF α Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30579-50, RA30579-100

Citations, Manuals and MSDS Available upon request.

Background: tumor necrosis factor (TNF) Homo sapiens This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB: 1:500-1:2000 IHC: 1:50-1:200

Alternative Names: Tumor necrosis factor (Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2;TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment;NTF) ; Intracellular domain 1 (ICD1) ; Intracellular domain 2 (ICD2) ; C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]

Applications: WB; IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 7124

Protein MW (KDa): 17,25

SWISS: P01375

Source: Rabbit

Research Use Only