Product Description

TNFSF18 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61856-50, BS61856-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: GITRL (glucocorticoid-induced TNF-related ligand), a polypeptide encoded by a human umbilical endothelial cell cDNA, is a member of the TNF (tumor necrosis factor) superfamily. GITRL has a type 2 transmembrane topology that is characteristic of the TNF family. The TNF superfamilies regμlate diverse biological functions, including cell proliferation, differentiation and survival. GITRL is found on vascμlar endothelial cells and in several peripheral tissues (small intestine, ovary, testis and kidney), where it may modμlate T lymphocyte survival. The GITR receptor recognizes GITRL and the two interact to regμlate NFκB activation. The ligand-receptor pair of GITRL-GITR protects cells against AICD (activation-induced cell death).

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Tumor necrosis factor ligand superfamily member 18, Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, hGITRL

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding Human TNFSF18.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TNFSF18 Polyclonal Antibody detects endogenous levels of TNFSF18 protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UNG2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only