Product Description

TNR8 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35422-50, RA35422-100

Citations, Manuals and MSDS Available upon request.

Background: TNF receptor superfamily member 8 (TNFRSF8) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 IHC-p: 50-200 ELISA 1:5000-20000

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 943

Protein MW (KDa): 65

SWISS: P28908

Source: Rabbit

Research Use Only