TOP1MT Rabbit pAb - A15559

TOP1MT Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A15559-20, A15559-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Rat

Protein Weight: 70kDa

Observed Molecular Weight: 70kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 116447

SWISS: Q969P6

Alternate Names: TOP1MT

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:200 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Cancer.

NCBI Alias: TOP1MT

Research Use Only