Product Description

TRH-R1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES7446-50, ES7446-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011],

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Applications: WB, IF, ELISA

Alternate Names: TRHR, Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human TRHR. AA range:195-244

Isotype: IgG

Target: TRH-R1

Specificity: TRH-R1 Polyclonal Antibody detects endogenous levels of TRH-R1 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Brain, Pituitary, Placenta,

Observed Band (KD): 50kD

Fields: Calcium signaling pathway, Neuroactive ligand-receptor interaction

Function: Function: Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system
Similarity: Belongs to the G-protein coupled receptor 1 family

Subcellular Location: Cell membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: TRHR

Protein Name: Thyrotropin-releasing hormone receptor

Mouse Gene ID: 22045

Mouse SwissProt Number: P21761

Rat Gene ID: 25570

Rat SwissProt Number: Q01717

Research Use Only