Product Description

TRI11 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES12575-50, ES12575-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human TRI11 AA range: 128-178

Isotype: IgG

Target: TRI11

Specificity: This antibody detects endogenous levels of TRI11 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Ubiquitous,

Molecular Weight (Da): 51kD

Function: Domain: The coiled-coil domain and the B30.2 domain are both necessary for interaction with humanin
Function: May have E3 ubiquitin ligase activity. May contribute to the regulation of the intracellular level of humanin or humanin-containing proteins through the proteasomal degradation pathway
Similarity: Belongs to the TRIM/RBCC family
Similarity: Contains 1 B box-type zinc finger
Similarity: Contains 1 B30.2/SPRY domain
Similarity: Contains 1 RING-type zinc finger
Subunit: Binds cytoplasmic tail of integrin alpha-1. Interacts with the humanin peptide
Tissue Specificity: Ubiquitous

Subcellular Location: Cytoplasm Nucleus

Storage and Stability: -20°C/1 year

Gene Name: TRIM11 RNF92

Protein Name: TRI11

Mouse Gene ID: 338364

Mouse SwissProt Number: Q99PQ2

Rat SwissProt Number: B1H278

Research Use Only