Product Description

Tsg 101 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20614-50, RA20614-100

Citations, Manuals and MSDS Available upon request.

Background: tumor susceptibility 101 (TSG101) Homo sapiens The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: TSG101; Tumor susceptibility gene 101 protein; ESCRT-I complex subunit TSG101

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat; Monkey

GeneID (Human): 7251

Protein MW (KDa): 44

SWISS: Q99816

Source: Rabbit

Research Use Only