TXNIP Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24289-20, A24289-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 44kDa
Observed Molecular Weight: 55kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 10628
SWISS: Q9H3M7
Alternate Names: THIF; VDUP1; ARRDC6; HHCPA78; EST01027; TXNIP
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Cancer, Tumor suppressors, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Carbohydrate metabolism.
NCBI Alias: TXNIP
Research Use Only