Product Description

TYDP2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES12476-50, ES12476-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human TYDP2 AA range: 261-311

Isotype: IgG

Target: TYDP2

Specificity: This antibody detects endogenous levels of TYDP2 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Widely expressed (PubMed:10764746), Highly expressed in various brain regions, including the frontal and occipital lobes, the hippocampus, the striatum and the cerebellum (PubMed:24658003),

Molecular Weight (Da): 40kD

Subcellular Location: Nucleus Nucleus, PML body Nucleus, nucleolus Cytoplasm Localizes to nucleolar cavities following stress, localization to nucleolus is dependent on PML protein, Cytoplasm (Microbial infection) In case of infection by picornavirus, relocalizes to cytoplasmic sites distinct from those containing viral proteins associated with RNA replication or encapsidation

Storage and Stability: -20°C/1 year

Gene Name: TDP2 EAP2 TTRAP AD-022

Protein Name: TYDP2

Mouse Gene ID: 56196

Mouse SwissProt Number: Q9JJX7

Rat Gene ID: 498749

Rat SwissProt Number: Q3T1H5

Research Use Only