Product Description

ULK2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES8527-50, ES8527-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: unc-51 like autophagy activating kinase 2(ULK2) Homo sapiens This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: ULK2 KIAA0623

Clonality: Polyclonal

Immunogen: Synthetic peptide from human protein at AA range: 930-1000

Isotype: IgG

Target: ULK2

Specificity: The antibody detects endogenous ULK2 protein

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Brain, Testis,

Observed Band (KD): 140kD

Fields: Autophagy - other, Autophagy - animal, mTOR signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases

Function: Catalytic Activity: ATP + a protein = ADP + a phosphoprotein
PTM: Autophosphorylated
Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily
Similarity: Contains 1 protein kinase domain

Subcellular Location: Cytoplasmic vesicle membrane, Peripheral membrane protein Localizes to pre-autophagosomal membrane

Storage and Stability: -20°C/1 year

Gene Name: ULK2 KIAA0623

Protein Name: unc-51-like kinase 2 (C. elegans)

Mouse Gene ID: 29869

Mouse SwissProt Number: Q9QY01

Research Use Only