Product Description

YB-1/YBX1 Polyclonal Antibody

Sizes: 120μL, 200μL

Catalogue Numbers: E-AB-92743-120, E-AB-92743-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: YB-1/YBX1

Target Synonym: YBX1; BP-8; CBF-A; CSDA2; CSDB; DBPB; EFI-A; MDR-NF1; NSEP-1; NSEP1; YB-1; YB1

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells, Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P67809

Background: This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human YB-1/YBX1

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Calculated MW: 35kDa

Observed MW: 50kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only