Product Description

YTHD2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36296-50, RA36296-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: YTH N6-methyladenosine RNA binding protein 2 (YTHDF2) Homo sapiens This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 63

Protein Molecular Weight (kDa): 63

Storage: -20°C/1 year

Human Gene ID: 51441

Human SwissProt Number: Q9Y5A9

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only