Product Description

ZBT7A Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36340-50, RA36340-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'., similarity:Contains 1 BTB (POZ) domain., similarity:Contains 4 C2H2-type zinc fingers., subunit:Interacts with BCL6., tissue specificity:Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 64

Protein Molecular Weight (kDa): 64

Storage: -20°C/1 year

Human Gene ID: 51341

Human SwissProt Number: O95365

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only