Product Description

ZEP2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES12216-50, ES12216-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human ZEP2 AA range: 1975-2025

Isotype: IgG

Target: ZEP2

Specificity: This antibody detects endogenous levels of ZEP2 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in brain and skeletal muscle,

Molecular Weight (Da): 269kD

Function: Function: This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation
Induction: By mitogens and phorbol ester
Similarity: Contains 4 C2H2-type zinc fingers
Subunit: Interacts with TCF4
Tissue Specificity: Expressed in brain and skeletal muscle

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: HIVEP2

Protein Name: ZEP2

Mouse Gene ID: 15273

Mouse SwissProt Number: Q3UHF7

Rat Gene ID: 29721

Rat SwissProt Number: Q00900

Research Use Only