Product Description

ZKSC1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES12200-50, ES12200-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Zinc finger protein with KRAB and SCAN domains 1 (Zinc finger protein 139) (Zinc finger protein 36) (Zinc finger protein KOX18)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human ZKSC1 AA range: 313-363

Isotype: IgG

Target: ZKSC1

Specificity: This antibody detects endogenous levels of ZKSC1 at Human/Mouse/Rat

Dilution: WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.112% sodium azide.

Expression: Brain, Epithelium, Eye, Fetal kidney, Insulinoma, Lung, Lymphoid, Pancreas, Spleen,

Observed Band (KD): 60kD

Function: Function: May be involved in transcriptional regulation
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 1 KRAB domain
Similarity: Contains 1 SCAN box domain
Similarity: Contains 6 C2H2-type zinc fingers

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: ZKSCAN1 KOX18 ZNF139 ZNF36

Protein Name: ZKSC1

Mouse Gene ID: 74570

Mouse SwissProt Number: Q8BGS3

Rat Gene ID: 498160

Rat SwissProt Number: Q4KLI1

Research Use Only