β-1, 4-Gal-T2 rabbit pAb - ES7862

β-1, 4-Gal-T2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7862-50, ES7862-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is one of seven beta-1, 4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1, 4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity i

Alternate Name: B4GALT2; Beta-1; 4-galactosyltransferase 2; Beta-1, 4-GalTase 2; Beta4Gal-T2; b4Gal-T2; UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 2; UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 2

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from the C-terminal region of human β-1, 4-Gal-T2.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 8704

Human SWISS Prot NO: O60909

Subcellular Location: Golgi apparatus Golgi stack membrane; Single-pass type II membrane protein. Trans cisternae of Golgi stack.

Research Use Only