14-3-3 ζ rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES1543-50, ES1543-100
Citations, Manuals and MSDS Available upon request.
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008],
Alternate Name: YWHAZ; 14-3-3 protein zeta/delta; Protein kinase C inhibitor protein 1; KCIP-1
Source: Rabbit
Applications: WB; IHC; IP; IF; ELISA
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Reactivity: Human; Mouse; Rat
Immunogen: The antiserum was produced against synthesized peptide derived from human 14-3-3 zeta. AA range:24-73
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band (KD): 28kD
Human Gene ID: 7534
Human SWISS Prot NO: P63104
Subcellular Location: Cytoplasm. Melanosome. Located to stage I to stage IV melanosomes.
Research Use Only