14-3-3 θ rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES1544-50, ES1544-100
Citations, Manuals and MSDS Available upon request.
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008],
Alternate Name: YWHAQ; 14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
Source: Rabbit
Applications: WB; IHC; IF; ELISA
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Reactivity: Human; Mouse; Rat
Immunogen: The antiserum was produced against synthesized peptide derived from human 14-3-3 thet. AA range:41-90
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band (KD): 28kD
Human Gene ID: 10971
Human SWISS Prot NO: P27348
Subcellular Location: Cytoplasm. In neurons, axonally transported to the nerve terminals.
Research Use Only