Product Description

14-3-3 σ Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21466-50, RA21466-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway., function:p53-regulated inhibitor of G2/M progression., similarity:Belongs to the 14-3-3 family., subcellular location:May be secreted by a non-classical secretory pathway., subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN., tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: SFN, HME1, 14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin

Clonality: Polyclonal

Dilution: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight: 30

Protein Molecular Weight (kDa): 30

Storage: -20°C/1 year

Human Gene ID: 2810

Human SwissProt Number: P31947

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only