Product Description

8-OHdG (DNA/RNA Damage) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS66180-50, BS66180-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecμles that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: ELISA, IHC, IF

Alternate Names: 8-hydroxy-2'-deoxyguanosine, 2'-Deoxy-8-oxoguanosine, 7, 8-Dihydro-8-oxo-2'-deoxyguanosine, 8-Oxo-7, 8-dihydro-2'-deoxyguanosine, 8-Oxo-7, 8-dihydrodeoxyguanosine, 2'-Deoxy-8-oxo-D-guanosine, 8-Oxo-7, 8-dihydro-2μ-deoxyguanosine, 8-Oxo-dG, 2'-Deoxy-8-hydroxyguanosine

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: KLH conjugated 8-OHdG

Dilution: ELISA=1:5000-10000 IHC=1:100-500 IF=1:100-500

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: 8-OHdG (DNA/RNA Damage) polyclonal antibody detects endogenous levels of 8-OHdG protein.

Molecular Weight: ~ 0.283 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only