A Cyclase V/VI Polyclonal Antibody - BT-AP00054

A Cyclase V/VI Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00054-20, BT-AP00054-50, BT-AP00054-100

Citations, Manuals and MSDS Available upon request.

Background: ADCY5 encodes a member (adenylate cyclase 5) of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for ADCY5.

Research Areas: Others

Target Protein: ADCY6

Applications: IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: A Cyclase V/VI Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 138908

UniProt Accession: Human: O95622/O43306; Rat: Q04400/Q03343

Synonyms: ADCY6; KIAA0422; Adenylate cyclase type 6; ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca(2+)-inhibitable adenylyl cyclase; ADCY5; Adenylate cyclase type 5; ATP pyrophosp

GeneID: Human: 111/112; Mouse: 224129/11512; Rat: 64532

Research Use Only