AAAS Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS8208-50, BS8208-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9NRG9
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IF
All Applications: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: Aladin (Adracalin) belongs to a family of WD repeat-containing proteins. These proteins have a wide variety of functions, including signal transduction regulation, RNA processing and transcription. Aladin plays a role in peripheral and central nervous system development. It is widely expressed, with the highest expression seen in pituitary gland, corpus callosum, cerebellum, adrenal gland and gastrointestinal structures. Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterized by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: AAAS polyclonal antibody detects endogenous levels of AAAS protein.
Bioworld Molecular Weight: ~ 60 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western Blot (WB) analysis of AAAS polyclonal antibody
Alternative Name: Aladin; Adracalin; AAAS; ADRACALA; GL003
Immunogen: Recombinant full length Human AAAS.
Conjugate: Unconjugated
Modification: Unmodified