AAMP Polyclonal Antibody
Catalogue Numbers: BS61297-50, BS61297-100
Sizes: 50µl, 100µl
Alternative Name: Angio-associated migratory cell protein; AAMP;
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q13685
Host: Rabbit
Reactivity: Human, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. AAMP (angio-associated migratory cell protein) is a 434 amino acid immunoglobulin-like protein that contains 8 WD repeats. Expressed in endothelial cells, cytotrophoblasts and blood vessels, AAMP is thought to have a heparin-sensitive role in cell adhesion and cell migration. AAMP is strongly expressed in poorly differentiated colon adenocarcinoma cells, suggesting a role for AAMP in tumor progression.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: AAMP polyclonal antibody detects endogenous levels of AAMP protein.
Bioworld Molecular Weight: ~ 47 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of AAMP polyclonal antibody at 1:500 dilution
Lane 1: H9C2whole cell lysate Lane 2: A549 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human AAMP.
Conjugate: Unconjugated
Modification: Unmodified