ABCA8 (F1195) Polyclonal Antibody
Catalogue Numbers: BS3082-50, BS3082-100
Sizes: 50µl, 100µl
Alternative Name: ATP-binding cassette sub-family A member 8; KIAA0822
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: O94911
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes by harnessing the energy of ATP hydrolysis. ABCA8 (ATP-binding cassette, sub-family A (ABC1), member 8) is a 1,581 amino acid multi-pass membrane protein that contains two ABC transporter domains and belongs to the ABC transporter family. Expressed in a variety of tissues with particularly high expression in liver, heart and skeletal muscle, ABCA8 functions as an ATP-dependent lipophilic drug transporter that exists as multiple alternatively spliced isoforms.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ABCA8 (F1195) polyclonal antibody detects endogenous levels of ABCA8 protein.
Bioworld Molecular Weight: ~ 179 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ABCA8 (F1195) pAb at 1:500 dilution
Lane 1: H9C2 whole cell lysate(40ug)
Lane 2: AML-12 whole cell lysate(40ug)
Lane 3: SK-OVCAR3 whole cell lysate(40ug)
Lane 4: HepG2 whole cell lysate(40ug)
Lane 5: L02 whole cell lysate(10ug)
Immunogen: Synthetic peptide, corresponding to amino acids 1171-1220 of Human ABCA8.
Conjugate: Unconjugated
Modification: Unmodified